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NOOTROPICS

PE22-28 — next-gen antidepressant peptide

Also known as: Spadin analog

PE22-28 is a shortened, optimised Spadin analog. In mouse studies it produced antidepressant effects in 4 days by blocking the TREK-1 potassium channel.

99%+ purity · Janoshik HPLC verified
PE22-28 vial

Prices

PE22-28 · 10mg
1 vial30€
5-pack120€
Order via Discord

Mechanism

Selective TREK-1 blocker, increasing serotonergic activity for rapid antidepressant action.

Data

Mazella 2010: matched fluoxetine efficacy with faster onset in mouse models.

Frequently asked questions

Buy in EU?

Yes — research-grade only, EU shipping.

Research use only. Not for human consumption.